Hormones and Menopause, the symptoms and the benefits of CBD
Many women don’t realise they are entering the perimenopause stage, this is the early stages prior to menopause. Women start perimenopause at different ages, commonly in their 40’s, but can happen in the 30’s and sometimes earlier. Early signs of progression toward menopause are menstrual irregularity, breast tenderness, lower sex drive, fatigue, vaginal dryness and sometimes discomfort during sex.
Menopause is a result in falling and fluctuating oestrogen levels, the loss of oestrogen creates an imbalance of hormones, which ultimately results in an imbalance or a lack of estrogen, progesterone and testosterone throughout the body over time. The decline in hormones disrupts brain function, creates fat accumulation, and causing bone reabsorption.
Menopause changes each woman’s body differently and the experience of menopause is unique, no one experience is the same. Many factors can aid and help alleviate the symptoms of menopause from medically prescribed Hormone Replacement Therapy, to diet and lifestyle changes. CBD may also work in a range of ways to help perimenopause and menopause symptoms; due to the way it interacts with cannabinoid receptors.
The Endocannabinoid System refers to a collection of cell receptors called cannabinoid receptors, which are present in the brain, organs, and other tissues throughout the body. The endocannabinoid system works by interacting with chemical messengers, including CBD. Menopause seems to disrupt the endocannabinoid system, and there are cannabinoid receptors throughout the female reproductive system, so it is possible that CBD oil could reduce some of the symptoms relating to menopause.
CBD has been known to help with mood regulation, memory, insomnia, anxiety, joint pain, hot flushes and temperature regulation, and weight gain.
While there is currently no scientific evidence indicating that CBD oil or CBD products influence menopause symptoms, it could prove helpful for the following:
- Poor sleep and insomnia CBD’s influence on neurochemistry and anxiety could help improve sleep for women experiencing insomnia or poor sleep.
- Night Sweats and hot flushes Although there aren’t studies that have specifically tested CBD for hot flushes, its influence on the body’s serotonin system could be one reason why some women recommend CBD to their peeps for this symptom.
- Aches and Pains CBD has proven anti-inflammatory properties. In mice, CBD is anti-arthritic, protects joints against inflammatory damage, and lowers levels of inflammatory.
- Osteoporosis The same anti-inflammatory features that make CBD oil a popular remedy for arthritic symptoms might also prove useful for bone health. In rats with periodontitis, CBD lowers TNFα levels and prevents oral bone loss. However, we would advise you to talk to your GP and use every medical resource available if you’ve been diagnosed with low bone density.
- Bone Density Loss. Low bone density can increase the chance of fractures or bruises, an important symptom to treat. Some research has found that CBD interacts with a cannabinoid receptor that may play a role in bone density loss. CBD may therefore be able to reduce the rate of bone density loss that can occur during menopause.
- Weight Gain Cannabidiol could contribute by switching on genes for healthy metabolism and also helps buffer the activity of natural endocannabinoids, including 2-AG, which is linked to insulin resistance and ramped up during menopause.
- Mood swings CBD activates serotonin receptors similar to the anti-anxiety drug buspirone. Please read the following articles about the different ways that CBD could help anxiety or depression.)
CBD helps with health and fitness
- Promoting sleep We can all work out better and perform better when we sleep well, right? So if CBD oil can improve your sleep, it can indirectly improve your athletic performance. A review of research involving all types of cannabinoids and sleep found that there is evidence that CBD can directly affect sleep by interacting with related receptors in the brain. More research is needed, but there is definite potential for CBD to help people who struggle with sleep disorders and insomnia get more and better quality sleep.
- Relieving stress and anxiety Another indirect way that CBD oil may boost your athletic performance and confer some fitness benefits is by managing anxiety and stress. Most athletes know the nervousness that comes ahead of competitions and the stress that can be caused by putting a lot of pressure on working out and succeeding.These feelings may be alleviated by CBD oil. One study found that in people with anxiety disorders, treatment with CBD oil reduced nervousness, discomfort, and anxiety, and improved cognitive function ahead of a performance as compared to people who did not receive CBD oil.
- Reduces pain signals CBD has also been found to help with pain relief. One review found that CBD was effective in overall pain management in those with chronic pain, without adverse side effects. CBD modulates pain and the sensation of pain by stimulating the uptake of the neurotransmitter, adenosine, thereby boosting adenosine levels in the brain and inhibiting pain sensation. CBD may also block pain signals from reaching processing centres in the brain by binding to TPRV1, which is responsible for pain and inflammation.
Source Cannabinoids in the management of difficult to treat pain Published 2008
- Increases immune response CBD can modulate the immune response by decreasing levels of pro-inflammatory cytokines and inhibits the proliferation of T cells that are indicated in autoimmune and systemic inflammatory disorders.
Reduces inflammation CBD decreases oxidative stress and systemic inflammation by acting as an antioxidant. CBD may also decrease inflammation by preventing a reductions in micro elements like zinc and selenium which is are important factors for balanced immune response.
Any reduction in inflammation can reduce the pain associated with normal muscle pain after a tough workout as well as injuries. There is plenty of evidence from research that CBD can help reduce pain. The studies point to action at certain receptors but also a reduction in inflammation as explanations for how it works.
Like CBD, CBG has been used to combat pain without having the intoxicating effect of cannabinoids like THC. Research shows that CBG can also have therapeutic effects. However, human studies on this are sparse and more research needs to be done in this area.
Some promising animal studies show that CBG might ultimately be found useful for the following therapeutic benefits listed below:
IBD – Researchers induced inflammations similar to IBD in the colons of mice and then administered CBG. CBG was found to reduce inflammation and the production of nitric oxide. It also reduced the formation of reactive oxygen species (ROS) in the intestines. They concluded that CBG should be considered for clinical experimentation in IBD patients.
In preliminary studies, CBD oil has been shown to improve a variety of physical and mental health conditions like chronic pain, anxiety, ADHD, gastrointestinal illness, insomnia, cancer, and more. And in an April 2018 study of 60 children published in Neurology, a group of Israeli researchers found that CBD oil reduced autism-induced behavioural, communication, and anxiety problems.
The role of CBD for autism with anxiety is twofold. Firstly, some children with autism find that using CBD oil for anxiety alleviates not only stress but also aggression, self-injurious behaviours, and trouble with social interactions. Secondly, CBD oil can help children with co-occurring seizures. Of course, each child’s experience is unique, but in states where medical marijuana is illegal, parents are reporting positive CBD oil benefits for autism and epilepsy. Because cannabidiol CBD is not psychoactive, it is the option most parents prefer for their children over medical marijuana.
Many children with epilepsy find the same (or better) relief from their symptoms as they do with traditional anti-anxiety and anticonvulsant medications with the added bonus of fewer side effects. Researchers are still working to identify how CBD oil can help anxiety in autism, but for many families, the anecdotal evidence is enough for now.
Sourced and referenced from – ADI ARAN, Hanoch Cassuto, Asael Lubotzky
First published April 9, 2018
For those new to the world of CBD, a high-quality product like Nature-Drops is ideal, but it’s important to optimise the dosage for the desired effect, please contact us further if you have questions that cannot be found on our FAQ page.
Recent Research has linked CBD with benefits for the heart circulatory system. Studies indicate that CBD May be Able to help with high Blood pressure. One study treated 9 men with a dose of 600mg of CBD oil and found it to reduce resting Blood pressure comparing to a placebo.
May reduce acne
One study found that CBD oil prevented sebaceous land cells from secreting excessive sebum, exerted anti inflammatory actions and prevented the activation of pro acne agents like inflammatory cytokines
Might have neuroprotective properties
Studies on CBD shown many benefits in different neurological diseases such as:
- Alzheimer disease - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289988/
- Cognitive decline - https://pubmed.ncbi.nlm.nih.gov/25024347/
- Parkinson disease - https://pubmed.ncbi.nlm.nih.gov/24845114/
- Seizures and epilepsy - https://pubmed.ncbi.nlm.nih.gov/28538134/ - https://pubmed.ncbi.nlm.nih.gov/26724101/
- Multiple sclerosis https://pubmed.ncbi.nlm.nih.gov/24525548/
- Can alleviate cancer related symptoms
CBD can help to reduce symptoms related to cancer and Side effects related to cancer treatment like nausea, vomiting and pain.
CBD may help with chemotherapy induced nausea and vomiting. https://pubmed.ncbi.nlm.nih.gov/16983116/
E&OE July 2021